Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624803 | 0.90 | MRGPRX4 (0.47) | FFAR1SMN1; SMN2MAPTMRGPRX4KDM4E | |
| SCHEMBL16627150 | 0.84 | FFAR1 (0.47) | FFAR1FAAHCYP4F2CYP4A11CASP3 | |
| SCHEMBL17954293 | 0.81 | CYP11B1 (0.45) | FFAR1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL16628094 | 0.79 | CYP11B1 (0.45) | FFAR1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL16631062 | 0.78 | CYP11B1 (0.47) | FFAR1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL20101406 | 0.78 | FFAR1 (0.41) | FFAR1SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL16624805 | 0.77 | ACSS2 (0.42) | FFAR1SMN1; SMN2MAPTCYP4F2CYP4A11 | |
| SCHEMBL17954297 | 0.77 | FYN (0.43) | FFAR1SMN1; SMN2MAPTCYP4F2CYP4A11 | |
| SCHEMBL16624847 | 0.76 | CASP3 (0.50) | SMN1; SMN2MAPTTP53RAB9ARXFP1 | |
| SCHEMBL17954315 | 0.75 | CASP3 (0.46) | FFAR1SMN1; SMN2MAPTRAB9ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051045-A2 | 3'END CAPS FOR RNAi AGENTS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |