Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627388 | 0.85 | MAPT (0.45) | RAB9AMAPTNPC1SMN1; SMN2AHR | |
| SCHEMBL16627386 | 0.84 | RAB9A (0.56) | RAB9AMAPTNPC1SMN1; SMN2AHR | |
| SCHEMBL16627385 | 0.84 | DHODH (0.56) | RAB9AMAPTNPC1SMN1; SMN2AHR | |
| SCHEMBL16627384 | 0.81 | RAB9A (0.60) | RAB9AMAPTNPC1SMN1; SMN2MEN1 | |
| SCHEMBL16627387 | 0.80 | MAPT (0.44) | RAB9AMAPTNPC1SMN1; SMN2AHR | |
| SCHEMBL16627389 | 0.74 | MEN1 (0.62) | RAB9AMAPTNPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL16625558 | 0.72 | DHODH (0.52) | RAB9AMAPTNPC1SMN1; SMN2AHR | |
| SCHEMBL16625555 | 0.72 | CYP3A4 (0.47) | RAB9AMAPTNPC1SMN1; SMN2AHR | |
| SCHEMBL16625564 | 0.71 | ALDH1A1 (0.50) | RAB9AMAPTNPC1SMN1; SMN2HPGD | |
| SCHEMBL16625563 | 0.71 | DHODH (0.42) | RAB9AMAPTNPC1SMN1; SMN2AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150099888-A1 | 2-Anilinonicotinyl Based Chalcones Useful As Potential Anticancer Agents and Process for Preparation Thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099888-A1 | 2-Anilinonicotinyl Based Chalcones Useful As Potential Anticancer Agents and Process for Preparation Thereof | HCCS, WEE2, WEE1 | RAB9A 1415/4885MAPT 2681/4885NPC1 1383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.