Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9925579 | 0.91 | DRD2 (0.48) | DRD2GNAI3GNAO1GNAI1 | |
| SCHEMBL14792301 | 0.85 | DRD2 (0.50) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL31345675 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2 | |
| SCHEMBL17308793 | 0.79 | DRD2 (0.45) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL11923 | 0.79 | HRH3 (0.46) | GNAI3GNAO1GNAI1 | |
| SCHEMBL20080252 | 0.78 | CARM1 (0.50) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL16625897 | 0.78 | ARG1 (0.35) | — | |
| SCHEMBL10129899 | 0.77 | — | — | |
| SCHEMBL9925447 | 0.77 | — | — | |
| SCHEMBL9925501 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050472-A1 | FUSED INDOLE COMPOUNDS AND METHODS OF USING SAME | OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOST'YU "PANACELA LABS" (RU) | 2015-04-09 | — | — | WO | disclosed |