Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.47 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.47 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.47 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21759457 | 0.87 | ABCG2 (0.49) | ABCG2HPGDALOX12L3MBTL1MAPT | |
| SCHEMBL5962635 | 0.85 | ALDH1A1 (0.62) | ABCG2MAPTROCK1MEN1KMT2A | |
| SCHEMBL16627387 | 0.81 | MAPT (0.44) | ABCG2HPGDALOX12L3MBTL1MAPT | |
| SCHEMBL1376342 | 0.80 | DHODH (0.56) | ABCG2L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL4810235 | 0.79 | MAPT (0.53) | ABCG2HPGDALOX12L3MBTL1MAPT | |
| SCHEMBL4807203 | 0.79 | ABCG2 (0.52) | ABCG2HPGDALOX12L3MBTL1MAPT | |
| SCHEMBL18388841 | 0.79 | ABCG2 (0.52) | ABCG2HPGDALOX12L3MBTL1MAPT | |
| SCHEMBL5962729 | 0.79 | VCAM1 (0.49) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL16627421 | 0.79 | MEN1 (0.44) | HPGDL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL9402324 | 0.79 | DHODH (0.57) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150099888-A1 | 2-Anilinonicotinyl Based Chalcones Useful As Potential Anticancer Agents and Process for Preparation Thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099888-A1 | 2-Anilinonicotinyl Based Chalcones Useful As Potential Anticancer Agents and Process for Preparation Thereof | HCCS, WEE2, WEE1 | ABCG2 289/4885HPGD 1283/4885ALOX12 2609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.