Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.77 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.77 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11922687 | 0.90 | CHRNB2 (0.72) | CHRNB2CHRNA4CHRNA7TDP1L3MBTL1 | |
| SCHEMBL13512579 | 0.88 | CHRNB2 (0.70) | CHRNB2CHRNA4CHRNA7TDP1L3MBTL1 | |
| SCHEMBL6674571 | 0.87 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA7TDP1L3MBTL1 | |
| SCHEMBL31044635 | 0.87 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA7TDP1L3MBTL1 | |
| SCHEMBL10028665 | 0.87 | CHRNB2 (0.85) | CHRNB2CHRNA4CHRNA7TDP1L3MBTL1 | |
| SCHEMBL9827841 | 0.84 | CHRNB2 (0.69) | CHRNB2CHRNA4CHRNA7RIPK1KDM4E | |
| SCHEMBL4862940 | 0.84 | CHRNB2 (0.69) | CHRNB2CHRNA4CHRNA7RIPK1KDM4E | |
| SCHEMBL30093157 | 0.83 | CHRNB2 (0.79) | CHRNB2CHRNA4CHRNA7TDP1L3MBTL1 | |
| SCHEMBL9674133 | 0.83 | CHRNB2 (0.67) | CHRNB2CHRNA4CHRNA7TDP1L3MBTL1 | |
| SCHEMBL16625906 | 0.81 | CHRNB2 (0.65) | CHRNB2CHRNA4CHRNA7RIPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050472-A1 | FUSED INDOLE COMPOUNDS AND METHODS OF USING SAME | OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOST'YU "PANACELA LABS" (RU) | 2015-04-09 | — | — | WO | disclosed |