Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.65 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.65 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13509698 | 0.89 | CHRNB2 (0.59) | CHRNB2CHRNA4CHRNA7LMNAMAPK1 | |
| SCHEMBL15699208 | 0.87 | CHRNB2 (0.69) | CHRNB2CHRNA4CHRNA7LMNAMAPK1 | |
| SCHEMBL13995348 | 0.85 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRNA7LMNAALDH1A1 | |
| SCHEMBL26239734 | 0.83 | CHRNB2 (0.53) | CHRNB2CHRNA4CHRNA7LMNAALDH1A1 | |
| SCHEMBL10028665 | 0.82 | CHRNB2 (0.85) | CHRNB2CHRNA4CHRNA7LMNAMAPK1 | |
| SCHEMBL16627431 | 0.81 | CHRNB2 (0.77) | CHRNB2CHRNA4CHRNA7LMNAMAPK1 | |
| SCHEMBL11116302 | 0.81 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRNA7LMNAMAPK1 | |
| SCHEMBL4862940 | 0.80 | CHRNB2 (0.69) | CHRNB2CHRNA4CHRNA7LMNAMAPK1 | |
| SCHEMBL9827841 | 0.80 | CHRNB2 (0.69) | CHRNB2CHRNA4CHRNA7LMNAMAPK1 | |
| SCHEMBL6674571 | 0.79 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA7LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050472-A1 | FUSED INDOLE COMPOUNDS AND METHODS OF USING SAME | OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOST'YU "PANACELA LABS" (RU) | 2015-04-09 | — | — | WO | disclosed |
| WO-2015050471-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USING SAME | OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOST'YU "PANACELA LABS" (RU) | 2015-04-09 | — | — | WO | disclosed |