Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627487 | 0.90 | DGAT1 (0.60) | DGAT1 | |
| SCHEMBL15522231 | 0.90 | DGAT1 (0.74) | DGAT1 | |
| SCHEMBL14062103 | 0.85 | DGAT1 (0.69) | DGAT1 | |
| SCHEMBL15733205 | 0.83 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL15522130 | 0.82 | DGAT1 (0.77) | DGAT1 | |
| SCHEMBL19481437 | 0.81 | DGAT1 (0.86) | DGAT1 | |
| SCHEMBL17238977 | 0.80 | DGAT1 (0.77) | DGAT1 | |
| SCHEMBL17921242 | 0.79 | DGAT1 (0.83) | DGAT1 | |
| SCHEMBL14061822 | 0.79 | DGAT1 (0.72) | DGAT1 | |
| SCHEMBL17921250 | 0.79 | DGAT1 (0.74) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049668-A1 | NOVEL COMPOUND AS A DIACYLGLYCEROL ACYLTRANSFERASE INHIBITOR | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2015-04-09 | — | — | WO | disclosed |