Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627460 | 0.90 | DGAT1 (0.71) | DGAT1 | |
| SCHEMBL20992137 | 0.83 | DGAT1 (0.82) | DGAT1 | |
| SCHEMBL15742797 | 0.81 | DGAT1 (0.65) | DGAT1 | |
| SCHEMBL15522231 | 0.80 | DGAT1 (0.74) | DGAT1 | |
| SCHEMBL21077583 | 0.79 | DGAT1 (0.67) | DGAT1 | |
| SCHEMBL21077584 | 0.79 | DGAT1 (0.66) | DGAT1 | |
| SCHEMBL14136655 | 0.79 | DGAT1 (0.64) | DGAT1 | |
| SCHEMBL14136875 | 0.78 | DGAT1 (0.77) | DGAT1 | |
| SCHEMBL15733051 | 0.78 | DGAT1 (0.82) | DGAT1 | |
| SCHEMBL21077603 | 0.77 | DGAT1 (0.59) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049668-A1 | NOVEL COMPOUND AS A DIACYLGLYCEROL ACYLTRANSFERASE INHIBITOR | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2015-04-09 | — | — | WO | disclosed |