Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 12/20 | 0.67 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627720 | 0.86 | P2RX7 (0.71) | P2RX7P2RX4HDAC1CNR2HDAC11 | |
| SCHEMBL16627907 | 0.86 | P2RX7 (0.79) | P2RX7P2RX4HDAC1SMN1; SMN2 | |
| SCHEMBL16627864 | 0.85 | P2RX7 (0.60) | P2RX7P2RX4HDAC1P2RX3 | |
| SCHEMBL16627904 | 0.84 | P2RX7 (0.77) | P2RX7P2RX4HDAC1CNR2HDAC11 | |
| SCHEMBL16627672 | 0.84 | P2RX7 (0.76) | P2RX7P2RX4HDAC1P2RX2HDAC11 | |
| SCHEMBL16627629 | 0.82 | P2RX7 (0.60) | P2RX7P2RX4HDAC1P2RX3HDAC11 | |
| SCHEMBL16627865 | 0.82 | P2RX7 (0.58) | P2RX7P2RX4P2RX3 | |
| SCHEMBL16627911 | 0.82 | P2RX7 (0.51) | P2RX7P2RX4HDAC1P2RX3HDAC11 | |
| SCHEMBL16627908 | 0.82 | P2RX7 (0.91) | P2RX7P2RX4HDAC1CNR2HDAC11 | |
| SCHEMBL16627607 | 0.80 | P2RX7 (0.79) | P2RX7P2RX2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |