Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 10/20 | 0.79 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627904 | 0.92 | P2RX7 (0.77) | P2RX7HDAC1P2RX4MAPTTP53 | |
| SCHEMBL16627672 | 0.91 | P2RX7 (0.76) | P2RX7HDAC1P2RX4MAPTTP53 | |
| SCHEMBL16627908 | 0.89 | P2RX7 (0.91) | P2RX7HDAC1P2RX4MAPTTP53 | |
| SCHEMBL16627720 | 0.89 | P2RX7 (0.71) | P2RX7HDAC1EDNRBP2RX4MAPT | |
| SCHEMBL16627607 | 0.87 | P2RX7 (0.79) | P2RX7FABP4MAPTTP53RXFP1 | |
| SCHEMBL16627605 | 0.86 | P2RX7 (0.77) | P2RX7 | |
| SCHEMBL16627628 | 0.86 | P2RX7 (0.67) | P2RX7HDAC1P2RX4SMN1; SMN2 | |
| SCHEMBL16627721 | 0.81 | P2RX7 (0.75) | P2RX7HDAC1P2RX4MAPTTP53 | |
| SCHEMBL16627793 | 0.78 | P2RX7 (0.80) | P2RX7HDAC1EDNRBP2RX4MAPT | |
| SCHEMBL16627612 | 0.77 | P2RX7 (1.00) | P2RX7P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |