Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | PARP1 | P09874 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 4/20 | 0.43 |
| ▸ | DDO | Q99489 | 3/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29471220 | 0.83 | BRD4 (0.53) | KDM4EPARP1ALDH1A1MEN1TNKS | |
| SCHEMBL26551030 | 0.83 | BRD4 (0.53) | KDM4EPARP1ALDH1A1MEN1TNKS | |
| SCHEMBL15690473 | 0.83 | DAO (0.65) | KDM4EPARP1ALDH1A1MEN1TNKS | |
| SCHEMBL30480858 | 0.80 | DAO (0.54) | KDM4EPARP1ALDH1A1MEN1TNKS | |
| SCHEMBL12277902 | 0.79 | MEN1 (0.62) | KDM4EPARP1ALDH1A1MEN1TNKS | |
| SCHEMBL15690324 | 0.79 | GRIN2D (0.51) | KDM4EALDH1A1MEN1CYP1A2KMT2A | |
| SCHEMBL30480899 | 0.78 | GRIK1 (0.47) | KDM4EPARP1ALDH1A1MEN1LMNA | |
| SCHEMBL709815 | 0.73 | PDE3B (0.52) | KDM4EPARP1ALDH1A1LMNACYP1A2 | |
| SCHEMBL29594580 | 0.73 | PDE3B (0.52) | KDM4EPARP1ALDH1A1LMNACYP1A2 | |
| SCHEMBL470317 | 0.73 | AHR (0.45) | KDM4EPARP1ALDH1A1GPR3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |