Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.54 |
| ▸ | DDO | Q99489 | 2/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627652 | 0.80 | KDM4E (0.45) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL22571313 | 0.80 | DAO (0.61) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL29471220 | 0.79 | BRD4 (0.53) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL26551030 | 0.79 | BRD4 (0.53) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL23714709 | 0.77 | PARP1 (0.42) | DAODDOKDM4EALDH1A1HRH4 | |
| SCHEMBL15690473 | 0.76 | DAO (0.65) | DAODDOKDM4EALDH1A1HRH4 | |
| SCHEMBL15690324 | 0.75 | GRIN2D (0.51) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL25203298 | 0.74 | KDM4E (0.56) | RAB9AKDM4EALDH1A1PDE3BPDE3A | |
| SCHEMBL12277902 | 0.72 | MEN1 (0.62) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL31154599 | 0.72 | KDM4E (0.66) | DAODDOKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116368128-A | Heterocyclic compounds as CBP/EP300 bromodomain inhibitors | 奥瑞基尼肿瘤有限公司 | 2023-06-30 | — | — | CN | disclosed |