Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 6/20 | 1.00 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | CBR1 | P16152 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627820 | 0.90 | AHR (1.00) | AHRMAOAMAOBMEN1NPC1 | |
| SCHEMBL30237030 | 0.89 | AHR (0.85) | AHRMAOAMAOBMEN1NPC1 | |
| SCHEMBL1397253 | 0.89 | AHR (0.85) | AHRMAOAMAOBMEN1NPC1 | |
| SCHEMBL16627821 | 0.88 | AHR (0.83) | AHRMAOAMAOBMEN1NPC1 | |
| SCHEMBL25221402 | 0.88 | AHR (0.78) | AHRMAOBNPC1RAB9ATP53 | |
| SCHEMBL30395213 | 0.88 | AHR (0.78) | AHRMAOBNPC1RAB9ATP53 | |
| SCHEMBL16627752 | 0.87 | AHR (0.81) | AHRMAOAMAOBMEN1NPC1 | |
| SCHEMBL16627668 | 0.85 | AHR (0.77) | AHRMAOAMAOBMEN1NPC1 | |
| SCHEMBL30237205 | 0.85 | AHR (1.00) | AHRMAOBMEN1NPC1RAB9A | |
| SCHEMBL25224642 | 0.85 | AHR (1.00) | AHRMAOBMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479822-B2 | AHR agonists | ELI LILLY AND COMPANY (US) | 2025-11-25 | — | — | US | disclosed |
| US-20230159493-A1 | AHR AGONISTS | ELI LILLY AND COMPANY | 2023-05-25 | — | — | US | disclosed |
| US-20230159493-A1 | AHR AGONISTS | ELI LILLY AND COMPANY | 2023-05-25 | — | — | US | disclosed |
| US-20230159493-A1 | AHR AGONISTS | ELI LILLY AND COMPANY | 2023-05-25 | — | — | US | disclosed |
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159493-A1 | AHR AGONISTS | AHR, ARNT, RORC | AHR 1/4885MAOA 953/4885MAOB 1146/4885 |
| US-12479822-B2 | AHR agonists | AHR, ARNT, RORC | AHR 1/4885MAOA 953/4885MAOB 1146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.