Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | DDO | Q99489 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168742 | 0.85 | NPC1 (0.66) | NPC1RAB9ALMNASMN1; SMN2SMYD3 | |
| SCHEMBL30395353 | 0.85 | NPC1 (0.66) | NPC1RAB9ALMNASMN1; SMN2SMYD3 | |
| SCHEMBL486475 | 0.84 | MAOB (0.56) | NPC1RAB9ALMNASMN1; SMN2SMYD3 | |
| SCHEMBL34468802 | 0.83 | MEN1 (0.54) | NPC1RAB9ALMNASMN1; SMN2SMYD3 | |
| SCHEMBL16627755 | 0.83 | MAOA (0.57) | NPC1RAB9ALMNASMN1; SMN2SMYD3 | |
| SCHEMBL16627875 | 0.83 | ADORA3 (0.53) | NPC1RAB9ALMNASMN1; SMN2SMYD3 | |
| SCHEMBL21639712 | 0.82 | MAOA (0.58) | NPC1RAB9ALMNASMN1; SMN2SMYD3 | |
| SCHEMBL16627888 | 0.82 | KDM4E (0.49) | SMYD3MAOBPADI4KMT2AMEN1 | |
| SCHEMBL16627887 | 0.80 | KDM4E (0.48) | NPC1RAB9ASMYD3PADI4KMT2A | |
| SCHEMBL34468752 | 0.80 | MAOB (0.60) | NPC1RAB9ALMNASMN1; SMN2SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |