Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | DDO | Q99489 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627856 | 0.83 | BRD4 (0.54) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL16627809 | 0.81 | BRD4 (0.51) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL7591960 | 0.77 | MMP2 (0.50) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL1772475 | 0.77 | BRD4 (0.46) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL16627871 | 0.76 | KDM4E (0.47) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL16627630 | 0.76 | SMYD3 (0.49) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL12909532 | 0.75 | BRD4 (0.59) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL28100952 | 0.72 | DAO (0.49) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL16627733 | 0.71 | MAPT (0.45) | BRD4DAODDOKDM4EALDH1A1 | |
| SCHEMBL12890517 | 0.71 | BRD4 (0.54) | BRD4DAODDOKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |