Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | DDO | Q99489 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627871 | 0.84 | KDM4E (0.47) | MAPTKDM4EALDH1A1GAAHIF1A | |
| SCHEMBL16627870 | 0.84 | DRD2 (0.45) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL16627873 | 0.84 | IDH1 (0.46) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL16627872 | 0.84 | CNR1 (0.52) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL16627734 | 0.81 | MEN1 (0.58) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9432629 | 0.79 | MEN1 (0.47) | MAPTKDM4EMEN1ALPGKMT2A | |
| SCHEMBL16627856 | 0.77 | BRD4 (0.54) | MAPTKDM4EALDH1A1GAAHIF1A | |
| SCHEMBL16627809 | 0.75 | BRD4 (0.51) | MAPTKDM4EALDH1A1GAAHIF1A | |
| SCHEMBL16627807 | 0.74 | MEN1 (0.52) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1772475 | 0.74 | BRD4 (0.46) | MAPTKDM4EALDH1A1GAAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |