Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | F12 | P00748 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | POLA1 | P09884 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168742 | 0.84 | NPC1 (0.66) | RAB9ASMN1; SMN2NPC1POLBF12 | |
| SCHEMBL30395353 | 0.84 | NPC1 (0.66) | RAB9ASMN1; SMN2NPC1POLBF12 | |
| SCHEMBL27015077 | 0.83 | F12 (0.49) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL486475 | 0.83 | MAOB (0.56) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL34468871 | 0.82 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL34468802 | 0.82 | MEN1 (0.54) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL16627875 | 0.82 | ADORA3 (0.53) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL16627755 | 0.82 | MAOA (0.57) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL21639712 | 0.81 | MAOA (0.58) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL34468752 | 0.79 | MAOB (0.60) | MAPTRAB9ASMN1; SMN2NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |