Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627849 | 0.85 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL3644717 | 0.85 | MAOB (0.56) | ALDH1A1SMN1; SMN2MEN1KMT2AMAOB | |
| SCHEMBL16627895 | 0.84 | MEN1 (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2AMAOB | |
| SCHEMBL16627620 | 0.83 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MEN1KMT2AMAOB | |
| SCHEMBL16627846 | 0.81 | KDM4E (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2AMAOB | |
| SCHEMBL16627840 | 0.81 | MEN1 (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2AMAOB | |
| SCHEMBL16627851 | 0.81 | MEN1 (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2AMAOB | |
| SCHEMBL16627641 | 0.78 | MEN1 (0.44) | ATMALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7349368 | 0.77 | BRD4 (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2APADI4 | |
| SCHEMBL16627822 | 0.76 | MAPT (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |