Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.72 |
| ▸ | ERG | P11308 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662891 | 0.84 | CRHR1 (0.66) | CRHR1ERG | |
| SCHEMBL3037677 | 0.84 | CRHR1 (1.00) | CRHR1ERG | |
| SCHEMBL1662822 | 0.81 | CRHR1 (0.61) | CRHR1ERG | |
| SCHEMBL14265099 | 0.81 | CRHR1 (0.94) | CRHR1ERG | |
| SCHEMBL13909087 | 0.80 | CRHR1 (0.92) | CRHR1ERG | |
| SCHEMBL1660713 | 0.80 | CRHR1 (0.63) | CRHR1ERG | |
| SCHEMBL1661744 | 0.79 | CRHR1 (0.59) | CRHR1ERG | |
| SCHEMBL14265102 | 0.78 | CRHR1 (1.00) | CRHR1ERG | |
| SCHEMBL4034909 | 0.78 | CRHR1 (0.90) | CRHR1ERG | |
| SCHEMBL14265096 | 0.77 | CRHR1 (1.00) | CRHR1ERG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2487177-A1 | PYRAZOLOXAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2012-08-15 | — | — | EP | disclosed |
| EP-2487177-A1 | PYRAZOLOXAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2012-08-15 | — | — | EP | disclosed |
| US-20110086898-A1 | PYRAZOLOOXAZOLE COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-04-14 | — | — | US | disclosed |
| US-20110086898-A1 | PYRAZOLOOXAZOLE COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-04-14 | — | — | US | disclosed |
| US-20110086898-A1 | PYRAZOLOOXAZOLE COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-04-14 | — | — | US | disclosed |
| WO-2011043387-A1 | PYRAZOLOXAZOLE COMPOUND | エーザイ・アール・アンド・ディー・マネジメント株式会社 (JP) | 2011-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086898-A1 | PYRAZOLOOXAZOLE COMPOUND | CRHR1, MC2R, CRHR2 | CRHR1 1/4885ERG 1544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.