Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12150085 | 1.00 | MEN1 (0.37) | MEN1KMT2AHTTALDH1A1L3MBTL1 | |
| SCHEMBL2119148 | 0.88 | HTT (0.44) | MEN1KMT2AHTTALDH1A1SLC6A2 | |
| SCHEMBL21447376 | 0.81 | CCR2 (0.41) | KMT2AALDH1A1SLC6A2CCR2GRIN2B | |
| SCHEMBL21439085 | 0.81 | CCR2 (0.41) | KMT2AALDH1A1SLC6A2CCR2GRIN2B | |
| SCHEMBL21447477 | 0.81 | CCR2 (0.41) | KMT2AALDH1A1SLC6A2CCR2GRIN2B | |
| SCHEMBL23435289 | 0.81 | CCR2 (0.41) | KMT2AALDH1A1SLC6A2CCR2GRIN2B | |
| SCHEMBL2117103 | 0.74 | SLC6A2 (0.36) | SLC6A2SLC6A4 | |
| SCHEMBL23356985 | 0.68 | LMNA (0.49) | MEN1KMT2AHTTALDH1A1CCR2 | |
| SCHEMBL23375794 | 0.68 | LMNA (0.49) | MEN1KMT2AHTTALDH1A1CCR2 | |
| SCHEMBL21447253 | 0.68 | LMNA (0.49) | MEN1KMT2AHTTALDH1A1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2626350-B1 | CYCLOPROPANE COMPOUND | EISAI R&D MAN CO LTD (JP) | 2015-04-15 | — | — | EP | disclosed |