SCHEMBL16628762

SCHEMBL16628762

COc1ccc(/C=C/C(=O)Oc2ccccc2-c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 2/20 0.59
TUBB P07437 2/20 0.59
TUBA3C P0DPH7 2/20 0.59
TUBA1B P68363 2/20 0.59
TUBA4A P68366 2/20 0.59
TUBB4B P68371 2/20 0.59
TUBB3 Q13509 2/20 0.59
TUBB2A Q13885 2/20 0.59
TUBB8 Q3ZCM7 2/20 0.59
TUBA3E Q6PEY2 2/20 0.59
TUBA1A Q71U36 2/20 0.59
TUBA1C Q9BQE3 2/20 0.59
TUBB6 Q9BUF5 2/20 0.59
TUBB2B Q9BVA1 2/20 0.59
TUBB1 Q9H4B7 2/20 0.59
KMT2A Q03164 7/20 0.58
RAB9A P51151 1/20 0.58
MEN1 O00255 4/20 0.56
MAPT P10636 3/20 0.56
BCHE P06276 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16628763 1.00 TUBB4A (0.59) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL16628765 0.95 KMT2A (0.60) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL5169415 0.87 ESR1 (0.58) KMT2ARAB9AMEN1MAPTF3
SCHEMBL5507667 0.87 ESR1 (0.58) KMT2ARAB9AMEN1MAPTF3
SCHEMBL16628764 0.86 KMT2A (0.57) KMT2ARAB9AMEN1MAPTATM
SCHEMBL23097438 0.85 KMT2A (0.63) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL2313379 0.85 KMT2A (0.63) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL2313377 0.85 KMT2A (0.63) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL7694732 0.83 KMT2A (0.69) KMT2AMEN1MAPTBCHECYP3A4
SCHEMBL7694734 0.83 KMT2A (0.69) KMT2AMEN1MAPTBCHECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2695878-B1 Multi-functional monomer having a photocreative group, alignment film for LCD using the monomer, and LCD comprising the alignment film LG CHEMICAL LTD (KR) 2015-06-10 EP disclosed
EP-2695877-B1 Multi-functional monomer having a photocreative group, alignment film for LCD using the monomer, and LCD comprising the alignment film LG CHEMICAL LTD (KR) 2015-04-15 EP disclosed