SCHEMBL16628764

SCHEMBL16628764

COc1ccc(-c2ccccc2)c(OC(=O)C=Cc2ccccc2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.57
MAPT P10636 4/20 0.57
MEN1 O00255 3/20 0.57
RAB9A P51151 3/20 0.57
NPC1 O15118 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.56
HTR1A P08908 1/20 0.52
LMNA P02545 2/20 0.51
RECQL P46063 1/20 0.51
ATM Q13315 1/20 0.51
ABCG2 Q9UNQ0 1/20 0.51
HDAC8 Q9BY41 1/20 0.51
HPGD P15428 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
MAOB P27338 2/20 0.50
ALDH1A1 P00352 1/20 0.50
HSPD1 P10809 1/20 0.50
TNFRSF1A P19438 1/20 0.50
HSPE1 P61604 1/20 0.50
CYP1B1 Q16678 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16628762 0.86 TUBB4A (0.59) KMT2AMAPTMEN1RAB9AHTR1A
SCHEMBL16628763 0.86 TUBB4A (0.59) KMT2AMAPTMEN1RAB9AHTR1A
SCHEMBL16628765 0.86 KMT2A (0.60) KMT2AMAPTMEN1RAB9AHTR1A
SCHEMBL17301255 0.81 HTR1A (0.60) KMT2AMAPTMEN1RAB9ANPC1
SCHEMBL5169415 0.81 ESR1 (0.58) KMT2AMAPTMEN1RAB9ANPC1
SCHEMBL5507667 0.81 ESR1 (0.58) KMT2AMAPTMEN1RAB9ANPC1
SCHEMBL4691601 0.80 KMT2A (0.71) KMT2AMAPTMEN1HTR1AATM
SCHEMBL4691603 0.80 KMT2A (0.71) KMT2AMAPTMEN1HTR1AATM
SCHEMBL8045874 0.80 MAPT (0.62) KMT2AMAPTMEN1RAB9ANPC1
SCHEMBL28993080 0.79 MAOB (0.67) KMT2AMAPTMEN1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2695878-B1 Multi-functional monomer having a photocreative group, alignment film for LCD using the monomer, and LCD comprising the alignment film LG CHEMICAL LTD (KR) 2015-06-10 EP disclosed
EP-2695877-B1 Multi-functional monomer having a photocreative group, alignment film for LCD using the monomer, and LCD comprising the alignment film LG CHEMICAL LTD (KR) 2015-04-15 EP disclosed