Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | STK17B | O94768 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PNLIP | P16233 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2166669 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 | |
| SCHEMBL16628829 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 | |
| SCHEMBL2164768 | 0.80 | KDM4E (0.49) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 | |
| SCHEMBL2164772 | 0.80 | KDM4E (0.49) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 | |
| SCHEMBL2164776 | 0.80 | KDM4E (0.49) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 | |
| SCHEMBL2167216 | 0.76 | MAPT (0.41) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL2314384 | 0.76 | MAPT (0.41) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL2314381 | 0.76 | MAPT (0.41) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL9564397 | 0.75 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 | |
| SCHEMBL6137729 | 0.74 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350036-B1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-04-15 | — | — | EP | disclosed |