Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096053 | 0.88 | ADORA3 (0.59) | ADORA3ADORA2AADORA1ADORA2BSMN1; SMN2 | |
| SCHEMBL3094118 | 0.87 | ADORA3 (0.58) | ADORA3KDM4EGLAALDH1A1GAA | |
| SCHEMBL3087918 | 0.85 | ADORA3 (0.62) | ADORA3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL16628741 | 0.85 | HTT (0.61) | ADORA3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3093862 | 0.85 | ADORA2A (0.62) | ADORA3KDM4EALDH1A1ADORA2AADORA1 | |
| SCHEMBL3081056 | 0.83 | ADORA2A (0.70) | ADORA3ALDH1A1MAPTADORA2AADORA1 | |
| SCHEMBL3093664 | 0.82 | ADORA3 (0.55) | ADORA3KDM4ETP53GLAALDH1A1 | |
| SCHEMBL3087861 | 0.82 | ADORA3 (0.65) | ADORA3ALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL16628820 | 0.82 | ADORA3 (0.68) | ADORA3KDM4ETP53ALDH1A1GAA | |
| SCHEMBL3081770 | 0.82 | ADORA3 (0.58) | ADORA3KDM4ETP53GLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164833-B1 | Quinazolinamide derivatives useful for the treatment of tumour diseases | MERCK PATENT GMBH (DE) | 2015-04-15 | — | — | EP | claimed |