Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MDM4 | O15151 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.47 |
| ▸ | CDC25B | P30305 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.46 |
| ▸ | TACR2 | P21452 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16628841 | 1.00 | L3MBTL1 (0.58) | L3MBTL1TP53MDM2POLBMDM4 | |
| SCHEMBL15514084 | 0.95 | TP53 (0.55) | L3MBTL1TP53MDM2POLBMDM4 | |
| SCHEMBL5840884 | 0.95 | TP53 (0.55) | L3MBTL1TP53MDM2POLBMDM4 | |
| SCHEMBL16967451 | 0.95 | TP53 (0.55) | L3MBTL1TP53MDM2POLBMDM4 | |
| SCHEMBL5840927 | 0.95 | TP53 (0.55) | L3MBTL1TP53MDM2POLBMDM4 | |
| SCHEMBL967053 | 0.92 | TP53 (0.50) | L3MBTL1TP53MDM2POLBMDM4 | |
| SCHEMBL967054 | 0.92 | TP53 (0.50) | L3MBTL1TP53MDM2POLBMDM4 | |
| SCHEMBL7582210 | 0.92 | TP53 (0.55) | L3MBTL1TP53MDM2POLBMDM4 | |
| SCHEMBL11173059 | 0.91 | TP53 (0.52) | L3MBTL1TP53MDM2POLBMDM4 | |
| SCHEMBL13491599 | 0.91 | POLB (0.52) | L3MBTL1TP53MDM2POLBMDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2578598-B1 | Componds derived from normuramyldipeptide | IMUTHES LTD (GB) | 2015-04-15 | — | — | EP | disclosed |