Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16629284 | 0.79 | GRN (0.49) | BRD4 | |
| SCHEMBL16629273 | 0.78 | BRD4 (0.35) | BRD4 | |
| SCHEMBL29664520 | 0.72 | BRD4 (0.36) | BRD4 | |
| SCHEMBL16629274 | 0.69 | BRD4 (0.34) | BRD4 | |
| SCHEMBL18019577 | 0.67 | BRD4 (0.35) | BRD4 | |
| SCHEMBL15273735 | 0.66 | AAK1 (0.35) | — | |
| SCHEMBL22445393 | 0.64 | CNR2 (0.32) | BRD4 | |
| SCHEMBL16629271 | 0.64 | BRD4 (0.38) | BRD4 | |
| SCHEMBL21872232 | 0.62 | BRD4 (0.36) | BRD4 | |
| SCHEMBL15273681 | 0.62 | AAK1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050989-A2 | MACROCYCLIC COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | CS THERAPEUTICS INC. (US) | 2015-04-09 | — | — | WO | disclosed |