Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662701 | 0.86 | HPGD (0.42) | HPGDGAASMN1; SMN2MAPTKDM4E | |
| SCHEMBL1662566 | 0.85 | MAPT (0.41) | HPGDGAASMN1; SMN2MAPTKDM4E | |
| SCHEMBL1662695 | 0.85 | SMURF2 (0.37) | HPGDGAASMN1; SMN2MAPTKDM4E | |
| SCHEMBL1662841 | 0.82 | MAPT (0.39) | HPGDGAASMN1; SMN2MAPTKDM4E | |
| SCHEMBL1663047 | 0.75 | HPGD (0.41) | HPGDGAASMN1; SMN2MAPTKDM4E | |
| SCHEMBL1663263 | 0.75 | HPGD (0.41) | HPGDGAASMN1; SMN2MAPTKDM4E | |
| SCHEMBL1662708 | 0.74 | HPGD (0.40) | HPGDGAASMN1; SMN2MAPTKDM4E | |
| SCHEMBL1662501 | 0.74 | HPGD (0.42) | HPGDGAASMN1; SMN2MAPTKDM4E | |
| SCHEMBL1662585 | 0.73 | KDM4E (0.44) | HPGDGAASMN1; SMN2MAPTKDM4E | |
| SCHEMBL1667525 | 0.70 | SMURF2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |