Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663047 | 0.88 | HPGD (0.41) | HPGDPOLBCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1662708 | 0.87 | HPGD (0.40) | HPGDPOLBCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1662501 | 0.87 | HPGD (0.42) | HPGDPOLBCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1662701 | 0.87 | HPGD (0.42) | HPGDPOLBCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1662841 | 0.79 | MAPT (0.39) | HPGDPOLBCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1662695 | 0.77 | SMURF2 (0.37) | HPGDPOLBCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1662551 | 0.77 | HPGD (0.47) | HPGDPOLBCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1663476 | 0.76 | ALDH1A1 (0.37) | HPGDPOLBCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1662566 | 0.75 | MAPT (0.41) | HPGDPOLBCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1662950 | 0.75 | HPGD (0.37) | HPGDPOLBCYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |