Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662708 | 0.90 | HPGD (0.40) | MAPTPOLBHPGDKDM4EALDH1A1 | |
| SCHEMBL1662695 | 0.84 | SMURF2 (0.37) | MAPTPOLBHPGDKDM4EALDH1A1 | |
| SCHEMBL1662950 | 0.82 | HPGD (0.37) | MAPTPOLBHPGDKDM4EALDH1A1 | |
| SCHEMBL1662566 | 0.82 | MAPT (0.41) | MAPTPOLBHPGDKDM4EALDH1A1 | |
| SCHEMBL1663047 | 0.79 | HPGD (0.41) | MAPTPOLBHPGDKDM4EALDH1A1 | |
| SCHEMBL1663263 | 0.79 | HPGD (0.41) | MAPTPOLBHPGDKDM4EALDH1A1 | |
| SCHEMBL1662701 | 0.78 | HPGD (0.42) | MAPTPOLBHPGDKDM4EALDH1A1 | |
| SCHEMBL1662501 | 0.78 | HPGD (0.42) | MAPTPOLBHPGDKDM4EALDH1A1 | |
| SCHEMBL1662760 | 0.77 | P2RX7 (0.40) | POLBHPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1664800 | 0.76 | P2RX7 (0.35) | POLBHPGDALDH1A1SMN1; SMN2CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |