SCHEMBL16631250

SCHEMBL16631250

Cc1[nH]c(=O)c(C)cc1[C@@H]1O[C@H](CO)C(O)[C@@H]1O

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 17/20 0.44
SLC5A1 P13866 7/20 0.43
SYNJ2 O15056 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16631254 0.88 SLC5A2 (0.38) SLC5A2SLC5A1SYNJ2
SCHEMBL16631248 0.86 SLC5A2 (0.43) SLC5A2SLC5A1SYNJ2
SCHEMBL16631432 0.86 TK2 (0.38) SLC5A2
SCHEMBL16631264 0.83 SLC5A2 (0.41) SLC5A2SLC5A1SYNJ2
SCHEMBL16631266 0.82 SLC5A2 (0.40) SLC5A2SLC5A1SYNJ2
SCHEMBL16631516 0.80 PYGL (0.44) SLC5A2SYNJ2
SCHEMBL18871288 0.79 SLC28A1 (0.46) SLC5A2
SCHEMBL16781808 0.79 SLC28A1 (0.46) SLC5A2
SCHEMBL16805397 0.79 SLC28A1 (0.46) SLC5A2
SCHEMBL16631246 0.79 SLC28A1 (0.46) SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160264614-A1 POLYNUCLEOTIDE MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2016-09-15 US disclosed
US-20160264614-A1 POLYNUCLEOTIDE MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2016-09-15 US disclosed
WO-2015051173-A2 POLYNUCLEOTIDE MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC (US) 2015-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160264614-A1 POLYNUCLEOTIDE MOLECULES AND USES THEREOF POLRMT, POLN, NSUN3 SLC5A2 3235/4885SLC5A1 3466/4885SYNJ2 642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.