Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HBB | P68871 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.40 |
| ▸ | PYGM | P11217 | 3/20 | 0.38 |
| ▸ | TK2 | O00142 | 3/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.36 |
| ▸ | TK1 | P04183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631606 | 0.88 | PYGM (0.53) | DNPH1PYGMTK2P2RY2TK1 | |
| SCHEMBL16631531 | 0.86 | TSHR (0.53) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL18464477 | 0.83 | TSHR (0.69) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL18080061 | 0.79 | P2RY6 (0.62) | DNPH1P2RY2 | |
| SCHEMBL16631591 | 0.76 | PYGM (0.55) | DNPH1PYGMTK2P2RY2TK1 | |
| SCHEMBL16631203 | 0.75 | TSHR (0.49) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL16631514 | 0.74 | PYGM (0.49) | DNPH1PYGMTK2P2RY2TK1 | |
| SCHEMBL16631628 | 0.74 | PYGM (0.53) | DNPH1PYGMTK2P2RY2TK1 | |
| SCHEMBL16631649 | 0.74 | PYGM (0.53) | MAPTDNPH1PYGMTK2P2RY2 | |
| SCHEMBL18081754 | 0.74 | CHRNE (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |