Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | HBB | P68871 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.40 |
| ▸ | TK2 | O00142 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.38 |
| ▸ | ESRRA | P11474 | 1/20 | 0.37 |
| ▸ | CD74 | P04233 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631584 | 0.88 | PYGM (0.51) | P2RY2TK2TK1DNPH1PYGM | |
| SCHEMBL16631531 | 0.82 | TSHR (0.53) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL16631213 | 0.82 | ADK (0.39) | LMNANOTUML3MBTL1ESRRACD74 | |
| SCHEMBL16631635 | 0.82 | TSHR (0.52) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL18080024 | 0.79 | P2RY2 (0.57) | P2RY2DNPH1 | |
| SCHEMBL16631690 | 0.76 | L3MBTL1 (0.47) | SMN1; SMN2NOTUML3MBTL1ESRRACD74 | |
| SCHEMBL18464477 | 0.76 | TSHR (0.69) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL16631317 | 0.75 | TSHR (0.53) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL16631274 | 0.74 | TSHR (0.52) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL16631629 | 0.73 | PYGM (0.52) | P2RY2TK2TK1DNPH1PYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |