Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631648 | 0.84 | LMNA (0.40) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL18080271 | 0.74 | P2RY2 (0.49) | — | |
| SCHEMBL16631645 | 0.73 | LMNA (0.39) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL16631489 | 0.73 | KDM4E (0.38) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL18081676 | 0.72 | P2RY6 (0.32) | — | |
| SCHEMBL16631702 | 0.66 | PNP (0.35) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL16631646 | 0.66 | PNP (0.35) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL16631860 | 0.66 | TSHR (0.33) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL16631258 | 0.66 | TSHR (0.33) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL16631644 | 0.65 | PNP (0.36) | LMNASMN1; SMN2TSHRMAPTPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |