Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SELL | P14151 | 1/20 | 0.32 |
| ▸ | SELP | P16109 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18080239 | 0.84 | KDM4E (0.41) | TSHRLMNAMAPTPMP22SMN1; SMN2 | |
| SCHEMBL16631394 | 0.77 | DGAT1 (0.34) | — | |
| SCHEMBL18080191 | 0.75 | KDM4E (0.40) | TSHRLMNAMAPTPMP22SMN1; SMN2 | |
| SCHEMBL16631315 | 0.75 | KDM4E (0.40) | TSHRLMNAMAPTPMP22SMN1; SMN2 | |
| SCHEMBL18080249 | 0.74 | P2RY2 (0.52) | — | |
| SCHEMBL16631860 | 0.74 | TSHR (0.33) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL16631605 | 0.72 | SELP (0.32) | SELLSELP | |
| SCHEMBL18081677 | 0.72 | — | — | |
| SCHEMBL16631931 | 0.72 | PARP1 (0.32) | — | |
| SCHEMBL18080224 | 0.71 | KDM4E (0.39) | TSHRLMNAMAPTPMP22SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |