Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18081761 | 0.82 | DAO (0.37) | PDE3BPDE3A | |
| SCHEMBL16631437 | 0.79 | MGAM (0.35) | MGAMGAASIMGAM2TYMP | |
| SCHEMBL18080452 | 0.79 | KDM5B (0.32) | — | |
| SCHEMBL16631519 | 0.75 | TNKS (0.35) | MGAMGAASIMGAM2TNKS2 | |
| SCHEMBL18081765 | 0.73 | TYMP (0.38) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL16631918 | 0.72 | SLC9A1 (0.35) | MGAMGAASIMGAM2TNKS2 | |
| SCHEMBL18081438 | 0.72 | — | — | |
| SCHEMBL18081931 | 0.72 | TNKS2 (0.34) | MGAMGAASIMGAM2TNKS2 | |
| SCHEMBL16631363 | 0.72 | — | — | |
| SCHEMBL16631536 | 0.71 | P2RX7 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |