Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18081778 | 0.80 | BRD4 (0.33) | — | |
| SCHEMBL18080518 | 0.79 | BTK (0.33) | BTK | |
| SCHEMBL16631522 | 0.70 | BRD4 (0.43) | MAPTKDM4EALDH1A1GRIN2DGRIN3B | |
| SCHEMBL18080522 | 0.66 | BTK (0.39) | BTK | |
| SCHEMBL16631893 | 0.65 | PYGL (0.40) | MAPTKDM4E | |
| SCHEMBL24836008 | 0.65 | PDE9A (0.36) | MAPTKDM4EALDH1A1KMT2ANOS3 | |
| SCHEMBL10326346 | 0.64 | NOS3 (0.44) | ALDH1A1KMT2ANOS3NOS1NOS2 | |
| SCHEMBL12462788 | 0.62 | CDC7 (0.44) | KDM4EALDH1A1KMT2ANOS3NOS1 | |
| SCHEMBL15335986 | 0.62 | KDM4E (0.51) | MAPTKDM4EALDH1A1RXFP1 | |
| SCHEMBL13153055 | 0.62 | DAO (0.54) | MAPTKDM4EALDH1A1NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |