Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 2/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | TK1 | P04183 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18081900 | 0.84 | MAPK1 (0.54) | CA9CA12MAPK1HPGD | |
| SCHEMBL18080407 | 0.81 | GRIN1 (0.39) | GRIN1GRIN2BCA9CA12CA1 | |
| SCHEMBL16631451 | 0.78 | CYP19A1 (0.53) | HPGD | |
| SCHEMBL16631717 | 0.74 | DDB1 (0.38) | GRIN1GRIN2BMAPK1DDB1CRBN | |
| SCHEMBL23957853 | 0.72 | MAPK1 (0.43) | GRIN1GRIN2BMAPK1HPGDDRD2 | |
| SCHEMBL16631398 | 0.70 | MAPK1 (0.51) | CA9CA12MAPK1EP300HPGD | |
| SCHEMBL7213260 | 0.70 | CYP1A2 (0.55) | MAPK1DRD2DRD3TK1CYP1A2 | |
| SCHEMBL16631548 | 0.70 | PYGM (0.38) | GRIN1GRIN2B | |
| SCHEMBL7821405 | 0.70 | HPGD (0.69) | MAPK1HPGDTK1 | |
| SCHEMBL18080366 | 0.69 | DDB1 (0.35) | GRIN1GRIN2BDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |