Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18081921 | 0.87 | HPGD (0.69) | CYP19A1HPGDHRH4AMY1A | |
| SCHEMBL18080415 | 0.84 | CYP19A1 (0.48) | CYP19A1HPGDHRH4AMY1ANPC1 | |
| SCHEMBL7821405 | 0.83 | HPGD (0.69) | HPGD | |
| SCHEMBL16631692 | 0.79 | CYP19A1 (0.50) | CYP19A1HRH4AMY1ANPC1RAB9A | |
| SCHEMBL16631404 | 0.78 | GRIN1 (0.41) | HPGD | |
| SCHEMBL18080377 | 0.77 | CYP19A1 (0.48) | CYP19A1HRH4AMY1ANPC1RAB9A | |
| SCHEMBL15014123 | 0.76 | CYP19A1 (0.76) | CYP19A1HRH4NPC1RAB9AALDH1A1 | |
| SCHEMBL7833489 | 0.74 | HPGD (0.64) | HPGD | |
| SCHEMBL16631915 | 0.74 | KCNMA1 (0.55) | CYP19A1HPGDHRH4AMY1ANPC1 | |
| SCHEMBL16631429 | 0.73 | SIRT2 (0.40) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |