Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 10/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.37 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18081594 | 0.90 | P2RY2 (0.45) | P2RY2ADORA3ADORA1DNPH1P2RY6 | |
| SCHEMBL16631311 | 0.82 | P2RY2 (0.41) | P2RY2ADORA3ADORA1DNPH1P2RY6 | |
| SCHEMBL18081592 | 0.80 | P2RY2 (0.42) | P2RY2DNPH1P2RY6P2RY14P2RY4 | |
| SCHEMBL16631541 | 0.80 | P2RY2 (0.55) | P2RY2ADORA3ADORA1 | |
| SCHEMBL18081589 | 0.78 | P2RY2 (0.46) | P2RY2DNPH1P2RY6P2RY14P2RY4 | |
| SCHEMBL18081597 | 0.77 | ADORA3 (0.40) | P2RY2ADORA3ADORA1P2RY6P2RY14 | |
| SCHEMBL18080023 | 0.77 | P2RY2 (0.59) | P2RY2P2RY6P2RY14P2RY4 | |
| SCHEMBL18081635 | 0.76 | P2RY2 (0.41) | P2RY2DNPH1P2RY6P2RY14P2RY4 | |
| SCHEMBL18081634 | 0.76 | P2RY2 (0.42) | P2RY2DNPH1P2RY6P2RY14P2RY4 | |
| SCHEMBL18081590 | 0.73 | P2RY2 (0.42) | P2RY2DNPH1P2RY6P2RY14P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |