Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 8/20 | 0.41 |
| ▸ | TK2 | O00142 | 1/20 | 0.40 |
| ▸ | TK1 | P04183 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631600 | 0.82 | P2RY2 (0.44) | P2RY2ADORA3ADORA1DNPH1P2RY6 | |
| SCHEMBL16631370 | 0.80 | ADORA3 (0.53) | P2RY2TK2TK1ADORA3ADORA1 | |
| SCHEMBL18080031 | 0.77 | P2RY2 (0.57) | P2RY2P2RY6P2RY14 | |
| SCHEMBL17359469 | 0.73 | DNPH1 (0.46) | P2RY2TK1DNPH1P2RY6P2RY14 | |
| SCHEMBL18844833 | 0.73 | DNPH1 (0.46) | P2RY2TK1DNPH1P2RY6P2RY14 | |
| SCHEMBL18081589 | 0.73 | P2RY2 (0.46) | P2RY2DNPH1P2RY6P2RY14 | |
| SCHEMBL15762146 | 0.73 | DNPH1 (0.47) | P2RY2TK1DNPH1P2RY6P2RY14 | |
| SCHEMBL16597023 | 0.73 | DNPH1 (0.47) | P2RY2TK1DNPH1P2RY6P2RY14 | |
| SCHEMBL16631334 | 0.72 | EIF4E (0.30) | — | |
| SCHEMBL16479411 | 0.72 | P2RY6 (0.54) | P2RY2DNPH1P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |