⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631231 | 0.85 | KDM4E (0.40) | — | |
| SCHEMBL16631647 | 0.79 | — | — | |
| SCHEMBL16631876 | 0.77 | TSHR (0.32) | — | |
| SCHEMBL18080199 | 0.75 | P2RY2 (0.49) | — | |
| SCHEMBL16631257 | 0.75 | SELP (0.33) | — | |
| SCHEMBL16631391 | 0.74 | OPRK1 (0.32) | — | |
| SCHEMBL16631244 | 0.74 | SELL (0.30) | — | |
| SCHEMBL16631467 | 0.74 | SLC5A2 (0.41) | — | |
| SCHEMBL16631468 | 0.74 | PYGL (0.40) | — | |
| SCHEMBL16631706 | 0.73 | NR1I3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |