Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 5/20 | 0.44 |
| ▸ | UMPS | P11172 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CDA | P32320 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18079907 | 1.00 | PYGL (0.44) | PYGLUMPSSLC5A2PNPHIF1A | |
| SCHEMBL16631242 | 0.88 | PYGL (0.37) | PYGLSLC5A2PNPMAPTCDA | |
| SCHEMBL16631834 | 0.86 | PYGL (0.36) | PYGLSLC5A2PNPMAPTCDA | |
| SCHEMBL16631306 | 0.84 | PYGL (0.44) | PYGLUMPSPNPHIF1AMAPT | |
| SCHEMBL16631243 | 0.81 | PYGL (0.40) | PYGLUMPSSLC5A2PNPHIF1A | |
| SCHEMBL16631239 | 0.81 | PYGL (0.42) | PYGLUMPSPNPHIF1AMAPT | |
| SCHEMBL18079925 | 0.77 | P2RY2 (0.53) | — | |
| SCHEMBL16631820 | 0.77 | UMPS (0.43) | PYGLUMPSSLC5A2PNPHIF1A | |
| SCHEMBL16631516 | 0.76 | PYGL (0.44) | PYGLSLC5A2PNPHIF1AMAPT | |
| SCHEMBL9116163 | 0.76 | PYGL (0.44) | PYGLUMPSSLC5A2PNPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |