Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18080420 | 0.85 | TYMP (0.32) | HTTEGLN2 | |
| SCHEMBL18081935 | 0.85 | MAPK1 (0.43) | TK1MAPK1 | |
| SCHEMBL18080418 | 0.75 | EP300 (0.33) | HTT | |
| SCHEMBL16631910 | 0.75 | MEN1 (0.31) | MAPK1MEN1KMT2A | |
| SCHEMBL18080395 | 0.75 | NTRK1 (0.32) | MEN1KMT2A | |
| SCHEMBL18080416 | 0.72 | TYMP (0.34) | TK1HTTMAPK1 | |
| SCHEMBL21954727 | 0.70 | MEN1 (0.32) | MEN1KMT2AEGLN2 | |
| SCHEMBL16631677 | 0.70 | MAPK1 (0.44) | TK1MAPK1 | |
| SCHEMBL16631483 | 0.70 | EGLN2 (0.40) | HTTMAPK1EGLN2 | |
| SCHEMBL23957853 | 0.69 | MAPK1 (0.43) | TK1MAPK1DRD2DRD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |