Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18080421 | 0.84 | KCNMA1 (0.42) | — | |
| SCHEMBL18080416 | 0.84 | TYMP (0.34) | TYMPHTT | |
| SCHEMBL18080420 | 0.84 | TYMP (0.32) | TYMPHTT | |
| SCHEMBL16631677 | 0.83 | MAPK1 (0.44) | EP300TYMP | |
| SCHEMBL18080405 | 0.82 | EP300 (0.39) | EP300CA9 | |
| SCHEMBL18080424 | 0.78 | CYP19A1 (0.43) | — | |
| SCHEMBL18080414 | 0.76 | TYMP (0.32) | TYMPHTT | |
| SCHEMBL16631711 | 0.75 | TK1 (0.33) | HTT | |
| SCHEMBL18080415 | 0.75 | CYP19A1 (0.48) | — | |
| SCHEMBL13384443 | 0.74 | SMN1; SMN2 (0.40) | TYMPHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | POLRMT, POLN, NSUN3 | EP300 4033/4885TYMP 40/4885HTT 505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.