Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 7/20 | 0.42 |
| ▸ | EDNRA | P25101 | 7/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956399 | 0.92 | EDNRB (0.41) | EDNRBEDNRASLC6A2TSPODRD3 | |
| SCHEMBL19582886 | 0.89 | EDNRA (0.39) | EDNRBEDNRASLC6A2TSPODRD3 | |
| SCHEMBL15427262 | 0.80 | CYP2D6 (0.39) | CYP2D6CYP3A4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL738509 | 0.79 | GBA1 (0.38) | EDNRBEDNRARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL16416281 | 0.78 | EDNRA (0.38) | EDNRBEDNRASLC6A2TSPODRD3 | |
| SCHEMBL13827717 | 0.78 | NPC1 (0.58) | CYP2D6CYP3A4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL285472 | 0.78 | HRH3 (0.45) | CYP2D6SMN1; SMN2KDM4ECYP2C19CYP1A2 | |
| SCHEMBL17003485 | 0.76 | EDNRA (0.37) | EDNRBEDNRASLC6A2TSPODRD3 | |
| SCHEMBL17003487 | 0.76 | EDNRA (0.37) | EDNRBEDNRASLC6A2TSPODRD3 | |
| SCHEMBL24042179 | 0.75 | CHRNB2 (0.43) | EDNRBEDNRASLC6A2TSPODRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | US | disclosed |
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | POLRMT, POLN, NSUN3 | EDNRB 1522/4885EDNRA 1751/4885CYP2D6 4668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.