SCHEMBL16631732

SCHEMBL16631732

CCc1cn(Cc2cn(CC)c(=O)nc2N)nn1

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 9/20 0.41
CYP19A1 P11511 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18081748 0.85 EP300 (0.40) EP300CYP19A1
SCHEMBL16631482 0.83 EP300 (0.40) EP300
SCHEMBL18080403 0.82 EP300 (0.36) EP300CYP19A1
SCHEMBL5201162 0.80 CDK1 (0.35) EP300
SCHEMBL16631397 0.72 EP300 (0.32) EP300
SCHEMBL18081911 0.69 EP300 (0.38) EP300
SCHEMBL16631731 0.69 KCNMA1 (0.54) EP300CYP19A1
SCHEMBL16631917 0.69 DPP4 (0.35) EP300
SCHEMBL18080404 0.68 KCNMA1 (0.52) CYP19A1
SCHEMBL9285404 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015051173-A2 POLYNUCLEOTIDE MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC (US) 2015-04-09 WO disclosed