Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PI4KA | P42356 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 3/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11718699 | 0.81 | EP300 (0.43) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL16631732 | 0.80 | EP300 (0.41) | EP300 | |
| SCHEMBL7195735 | 0.79 | TYR (0.35) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL12724345 | 0.79 | EP300 (0.43) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL24539176 | 0.79 | TET2 (0.40) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL19663162 | 0.78 | DHFR (0.33) | ALDH1A1DHFRTLR8KDM4ECYP1A2 | |
| SCHEMBL16631482 | 0.77 | EP300 (0.40) | EP300 | |
| SCHEMBL24797317 | 0.77 | CDK1 (0.33) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL19310476 | 0.75 | LMNA (0.47) | ALDH1A1EP300KDM4ECYP1A2CYP2D6 | |
| SCHEMBL16631397 | 0.74 | EP300 (0.32) | EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013013019-A2 | LYSOSOMAL POLYPEPTIDES, METHODS OF MAKING AND USING | ALNYLAM PHARMACEUTICALS, INC. (US) | 2013-01-24 | — | — | WO | disclosed |
| EP-1789586-A2 | DNA DECONTAMINATION METHOD | Roche Diagnostics GmbH (DE) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006024541-A2 | DNA DECONTAMINATION METHOD | ROCHE DIAGNOSTICS GMBH (DE) | 2006-03-09 | — | — | WO | disclosed |