Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RPA1 | P27694 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631760 | 0.86 | HTT (0.32) | HTTRPA1KDM4EALDH1A1 | |
| SCHEMBL18081793 | 0.84 | KDM4E (0.35) | KDM4EALDH1A1HPGD | |
| SCHEMBL18080564 | 0.78 | KDM4E (0.31) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16631770 | 0.74 | KDM4E (0.32) | HTTKDM4EALDH1A1HPGD | |
| SCHEMBL16631749 | 0.71 | HTT (0.33) | HTTKDM5B | |
| SCHEMBL18081777 | 0.70 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL16631657 | 0.69 | PYGM (0.36) | KDM4E | |
| SCHEMBL18080562 | 0.69 | CHEK1 (0.30) | — | |
| SCHEMBL18080571 | 0.65 | ALDH1A1 (0.33) | KDM4EALDH1A1HPGD | |
| SCHEMBL18080566 | 0.65 | KDM4E (0.30) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |