Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13788464 | 1.00 | OR51E2 (0.43) | OR51E2TSHRACHEMAPK1ALDH1A1 | |
| SCHEMBL822138 | 0.80 | ACHE (0.39) | TSHRACHEALDH1A1 | |
| SCHEMBL18175975 | 0.80 | OR51E2 (0.40) | OR51E2 | |
| SCHEMBL8766918 | 0.80 | OR51E2 (0.40) | OR51E2 | |
| SCHEMBL7769984 | 0.80 | OR51E2 (0.40) | OR51E2 | |
| SCHEMBL9001792 | 0.80 | TSHR (0.38) | TSHRACHEALDH1A1 | |
| SCHEMBL2559952 | 0.80 | OR51E2 (0.40) | OR51E2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL3790908 | 0.80 | GPR84 (0.36) | TSHRACHE | |
| SCHEMBL4183255 | 0.78 | OR51E2 (0.44) | OR51E2ALDH1A1 | |
| SCHEMBL5586417 | 0.78 | TSHR (0.37) | TSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |