Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631598 | 0.86 | LGALS3 (0.35) | TSHRLMNA | |
| SCHEMBL16631196 | 0.85 | TSHR (0.33) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL16631847 | 0.76 | — | — | |
| SCHEMBL16631218 | 0.74 | LGALS3 (0.35) | TSHRLMNA | |
| SCHEMBL16631402 | 0.74 | TSHR (0.36) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL16631241 | 0.73 | SYNJ2 (0.38) | TSHRLMNAMAPTPMP22SMN1; SMN2 | |
| SCHEMBL16631335 | 0.72 | TSHR (0.33) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL18081588 | 0.72 | — | — | |
| SCHEMBL16631821 | 0.70 | TNF (0.37) | TSHRLMNA | |
| SCHEMBL16631817 | 0.69 | TNF (0.36) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |